Interventions for the treatment of metastatic extradural spinal cord compression in adults
Abstract Background Metastatic extradural spinal cord compression (MESCC) is treated with radiotherapy, corticosteroids, and surgery, but there is uncertainty regarding their comparative effects. This is an updated version of the original Cochrane review published in theCochrane Database of Systematic Reviews (Issue 4, 2008). Objectives To determine the efficacy and safety of radiotherapy, surgery and corticosteroids […]
High-dose chemotherapy for children and young adults with stage IV rhabdomyosarcoma
Abstract Background Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Prognosis for patients with metastatic disease has not improved significantly in the past decades. High-dose chemotherapy (HDC) seems to be an attractive option to treat minimal residual disease in metastatic rhabdomyosarcoma patients. Objectives The objective of the review was to assess the effectiveness […]