Non-steroidal anti-inflammatory drugs for sciatica
Abstract Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently prescribed drugs for the treatment of sciatica. A previous Cochrane review on the efficacy of NSAIDs summarised findings for acute and chronic low back pain (LBP) and sciatica. This is an update of the original review (2008) focusing on people suffering from sciatica. […]
Paracetamol for low back pain
Abstract Background Analgesic medication is the most frequently prescribed treatment for low back pain (LBP), of which paracetamol (acetaminophen) is recommended as the first choice medication. However, there is uncertainty about the efficacy of paracetamol for LBP. Objectives To investigate the efficacy and safety of paracetamol for non-specific LBP. Search methods We conducted searches on […]
Hydromorphone for neuropathic pain in adults
Abstract Background Opioid drugs, including hydromorphone, are commonly used to treat neuropathic pain, and are considered effective by some professionals. Most reviews have examined all opioids together. This review sought evidence specifically for hydromorphone, at any dose, and by any route of administration. Other opioids are considered in separate reviews. This review is part of […]
Back schools for acute and subacute non-specific low-back pain
Abstract Background Since the introduction of the Swedish back school in 1969, back schools have frequently been used for treating people with low-back pain (LBP). However, the content of back schools has changed and appears to vary widely today. In this review we defined back school as a therapeutic programme given to groups of people, […]
Non-steroidal anti-inflammatory drugs for chronic low back pain
Abstract Background Chronic back pain is an important health problem. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat people with low back pain, especially people with acute back pain. Short term NSAID use is also recommended for pain relief in people with chronic back pain. Two types of NSAIDs are available and used to […]
Motor control exercise for acute non-specific low back pain
Abstract Background Motor control exercise (MCE) is used by healthcare professionals worldwide as a common treatment for low back pain (LBP). However, the effectiveness of this intervention for acute LBP remains unclear. Objectives To evaluate the effectiveness of MCE for patients with acute non-specific LBP. Search methods We searched MEDLINE, EMBASE, the Cochrane Central Register […]
Surgical versus non-surgical treatment for lumbar spinal stenosis
Abstract Background Lumbar spinal stenosis (LSS) is a debilitating condition associated with degeneration of the spine with aging. Objectives To evaluate the effectiveness of different types of surgery compared with different types of non-surgical interventions in adults with symptomatic LSS. Primary outcomes included quality of life, disability, function and pain. Also, to consider complication rates […]
Motor control exercise for chronic non-specific low-back pain
Abstract Background Non-specific low back pain (LBP) is a common condition. It is reported to be a major health and socioeconomic problem associated with work absenteeism, disability and high costs for patients and society. Exercise is a modestly effective treatment for chronic LBP. However, current evidence suggests that no single form of exercise is superior […]
Radiofrequency denervation for chronic low back pain
Abstract Background Radiofrequency (RF) denervation, an invasive treatment for chronic low back pain (CLBP), is used most often for pain suspected to arise from facet joints, sacroiliac (SI) joints or discs. Many (uncontrolled) studies have shown substantial variation in its use between countries and continued uncertainty regarding its effectiveness. Objectives The objective of this review […]
Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment
Abstract Background Manipulation and mobilisation are commonly used to treat neck pain. This is an update of a Cochrane review first published in 2003, and previously updated in 2010. Objectives To assess the effects of manipulation or mobilisation alone compared wiith those of an inactive control or another active treatment on pain, function, disability, patient […]